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Withania somnifera as a potential anxiolytic and immunomodulatory agent in acute sleep deprived female Wistar rats

T Kaur, H Singh, R Mishra, S Manchanda… - Molecular and cellular …, 2017 - Springer
Sleep is a profound regulator of cellular immunity, and the curtailment of sleep in present
day lifestyle leads to disruption of neuro-immune–endocrine interactions. No therapeutic
remedy is yet known for the amelioration of detrimental effects caused by sleep deprivation
(SD). The current study was aimed to elucidate the effects of acute SD on immune function
and its modulation by water extract from leaves of Withania somnifera (ASH-WEX). Three
groups of animals, ie Vehicle-Undisturbed sleep (VUD), Vehicle-Sleep deprived (VSD) and …
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Withania somnifera as a potential anxiolytic and immunomodulatory agent in acute sleep deprived female Wistar rats.

TK Taranjeet Kaur, HS Harpal Singh… - 2017 - cabidigitallibrary.org
Sleep is a profound regulator of cellular immunity, and the curtailment of sleep in present
day lifestyle leads to disruption of neuro-immune-endocrine interactions. No therapeutic
remedy is yet known for the amelioration of detrimental effects caused by sleep deprivation
(SD). The current study was aimed to elucidate the effects of acute SD on immune function
and its modulation by water extract from leaves of Withania somnifera (ASH-WEX). Three
groups of animals, ie Vehicle-Undisturbed sleep (VUD), Vehicle-Sleep deprived (VSD) and …
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